Longitudinal window imaging of a collapsing GC

With a widow implanted on the inguinal lymph node we can image the collapse of a germinal center. Antigen specific B cells (blue), Foxp3+ T cells (green) and follicular dendritic cells (red) can be visualized as the germinal center collapses.

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Foxp3+ T cells interacting with Macrophages in the GC

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T/B border interactions, pre GC formation